喻翠雲,出生于1978年10月,土家族,中共黨員,2003网站太阳集团教授,博士研究生導師,留美歸國學者,現任2003网站太阳集团院長,兼任新型抗體藥物及其智能運輸系統湖南省重點實驗室副主任。先後榮獲“全國三八紅旗手”“湖南省三八紅旗手”、“湖南省最美科技工作者”、湖南省自然科學傑出青年基金和湖南省委組織部優秀中青年專家等榮譽,牽頭湖南省第二屆“優秀研究生導師團隊”—藥劑學創新團隊和2003网站太阳集团“十二五”和“十三五”抗腫瘤藥物研發科技創新團隊牽頭人,入選第二輪高層次衛生人才“225”工程——湖南省醫學學科帶頭人、湖南省醫學學科骨幹人才、江蘇省“江海英才計劃”、2003网站太阳集团“船山人才工程”和2003网站太阳集团首批“青年英才計劃”。主持國家科技部重點研發計劃項目課題1項(2018YFB1900201),先後承擔湖南省重點研發計劃項目1項(2021SK2036),國家自然科學基金(含青年基金)2項(81471777、81102409)、湖南省自然科學基金傑出青年基金1項(2017JJ1024)等。在學術任職方面,擔任中國抗癌協會腫瘤微環境專業委員會委員、湖南省歐美同學會理事、湖南省藥學會第十五屆理事會理事、國家自然科學基金委員會評審專家、教育部評審專家、湖南省科技廳評審專家、2003网站太阳集团學術委員會委員,任Current Topics in Medicinal Chemistry雜志(SCI)客座主編等。主要創新性成果已經以第一作者/通訊作者身份在國際主流期刊如《Journal of Controlled Release》《ACS Applied Materials & Interfaces》、《Acta Biomaterialia》、《Molecular Pharmaceutics》等,累計以第一或通訊作者發表被SCI收錄30多篇,經檢索《ISI Web of Science》累計被引用逾600次,SCI“H-index”為15,被陳學思院士、美國三院院士Nicholas A. Peppasr等國内外知名專家大段引用、高度肯定,在國内外相關領域産生了重要的影響。已申請中國發明專利7項,授權4項;編寫專著7部,其中主編SCI期刊2期,副主編教材、專著各1部,參編3部。
近幾年主持的科研項目、課題:
1、湖南省重點研發計劃課題,2021SK2036,AS1411介導的球形核酸生物大分子藥物自傳遞體系關鍵技術研究,2021-2023,50-150,在研,主持。
2、國家重點研發計劃課題,2018YFB190020 1,放射性廢液膜蒸餾處理裝置研制應用,2019/04-2023/03,2895萬元,在研,主持。
3、湖南省自然科學傑出青年基金,2017JJ1024,生長抑素類似物修飾果膠-阿黴素納米藥物傳遞體系抗肝癌作用機制研究,2017/01-2019/12,30萬元,在研,主持。
4、國家自然科學基金項目,81471777,肝癌細胞靶向性藥物與miR-122共傳輸體系及其協同抗腫瘤作用機制研究,2015/01-2018/12,72萬元,已結題,主持。
5、湖南省科學技術廳課題,2014GK3082,用于5-FU和MiR-122共傳輸的半乳糖化殼聚糖基納米藥物載體研究,2014/01-2015/09,5萬元,已結題,主持。
6、國家自然科學基金項目,81102409,肝癌靶向性果膠基納米載藥體系的研究,2012/01-2014/12,20萬元,已結題,主持。
近幾年以通訊作者(含共同通訊作者)發表部分學術論文:
[1] Jinlei Peng, Ying Liu, Miao Zhang, Fangjun Liu, Liwei Ma, Cuiyun Yu*(通訊作者), Hua Wei*. One-pot fabrication of dual-redox sensitive, stabilized supramolecular nanocontainers for potential programmable drug release using a multifunctional cyclodextrin unit. J Control Release., 2021, 334, 290-302. (SCI, JCR Q1, IF= 9.776)
[2] Zhi Zheng, Ying Tan, Yi Li, Ying Liu, Guanghui Yi*, Cuiyun Yu*,(通訊作者)Hua Wei*. Biotherapeutic-loaded injectable hydrogels as a synergistic strategy to support myocardial repair after myocardial infarction. J Control Release., 2021, 335, 216-236. (SCI, JCR Q1, IF= 9.776)
[3] Xiao-Bo Nie, Cui-Yun Yu*(通訊作者), Hua Wei*. Precise modulation ofspatially distributed inorganic nanoparticles in block copolymers-based self-assemblies with diverse morphologies. Mater. Today Chem, 2021, 22. (SCI, JCR Q1, IF= 8.301)
[4] Zhi Zheng, Cuiyun Yu*(通訊作者),Hua Wei*. Injectable hydrogels as three-dimensional network reservoirs for osteoporosis treatment. Tissue Eng Part B Rev, 2021, 27(5) : 430-454. (SCI, JCR Q1, IF=6.389)
[5] Gui-Ying Kang, Wei Ma, Ming-Zhu Liu, Hai-Xi Luo, Cuiyun Yu*(通訊作者),Hua Wei* Expanding cyclic topology-based biomedical polymer panel:universal synthesis of hetero-"8"-shaped copolymers and topological modulation of polymer degradation. Macromol Rapid Commun, 2021, 42(17). (SCI, JCR Q1, IF=5.734)
[6] SiYue Tang, Hua Wei, CuiYun Yu *(通訊作者). Peptide-functionalized delivery vehicles for enhanced cancer therapy[J]. I Int J Pharm, 2021, 593 : 120141-.(SCI, JCR Q1, IF=5.873)
[7] Ya Xiang; Wen Huang; Cong Huang; Jinrong Long; Yangchun Zhou; Yufeng Liu; Siyue Tang, DongXiu He, XiangWen Tan, Hua Wei*, CuiYun Yu*(通訊作者). Facile fabrication of nanoparticles with dual-targeting ligands for precise hepatocellular carcinoma therapy in vitro and in vivo. Mol Pharm, 2020, 17(9) : 3223-3235. (SCI, JCR Q1, IF=4.939)
[8] Cheng-Hui Xu , Peng-Ju Yeab,Yang-Chun Zhou , Dong-Xiu Hea, Hua Wei *,Cui-Yun Yu*.(通訊作者)Cell membrane-camouflaged nanoparticles as drug carriers for cancer therapy. Acta Biomaterialia. 2020, 105, 1-14. (SCI, JCR Q1, IF=6.638)
[9] Mingqi Wang, Jinrong Long,Simin Zhang, Fangjun Liu, Xiaolong Zhang, Xianshuo Zhang, Lu Sun, Liwei Ma, Cuiyun Yu*(通訊作者)and Hua Wei*. Folate-targeted anticancer drug Delivery via a combination strategy of a micelle complex and reducible conjugation. ACS Biomater. Sci. Eng. 2020, 6, 1565-1572. (SCI, JCR Q1, IF=4.511)
[10] Yuping Liu, Yong Cong, Wei Ma, Guiying Kang, Chao Meng, Fangjun Liu, Cui yun Yu*(通訊作者)and Hua Wei*. Triple functional AB2 unit-modulated facile preparation of bioreducible hyperbranched copolymers. ACS Biomater. Sci. Eng. 2020, 6(5) : 2812-2821. (SCI, JCR Q2, IF=4.152)
[11] Lu Sun, Yang Zhou, Xufeng Zhou, Liwei Ma, Baoyan Wang, Cuiyun Yu*(通訊作者)and Hua Wei*. Synthesis of a triple-responsive double hydrophilic block copolymer prodrug using a reducible RAFT-ATRP double-head agent. ACS Applied Polymer Materials, 2020, 2(6) : 2126-2133. (SCI, JCR Q2, IF=4.089)
[12] Qian Ning, Yu-Feng Liu, Peng-Ju Ye, Pei Gao,Zhi-Ping Li ,SiYue Tang,Dong-Xiu He, Sheng-Song Tang,Hua Wei*and Cui-Yun Yu*.(通訊作者)Delivery of liver specific miRNA-122 using a targeted macromolecular prodrug toward synergistic therapy for hepatocellular carcinoma. ACS Applied Materials & Interfaces.2019, 11(11):10578-10588. (SCI, JCR Q1, IF=8.456)
[13] Guiying Kang, Lu Sun, Yuping Liu,Chao Meng, Wei Ma, Baoyan Wang, Liwei Ma, Cuiyun Yu*(通訊作者)and Hua Wei*. Micelles with cyclic poly(epsilon-caprolactone) moieties: greater stability, larger drug loading capacity, and slower degradation property for controlled drug release. Langmuir. 2019, 35, 12509−12517. (SCI, JCR Q2, IF=3.683)
[14] Xianshuo Zhangb Fangjun Liu, Xiaochen Li, Yunfei Tian, Liwei Ma, Cuiyun Yu*(通訊作者)and Hua Wei*.The fabrication of hybrid micelles with enhanced permeability for drug delivery via a diethoxymethylsilyl-based crosslinking strategy . Polym. Chem., 2019, 10,4529. (SCI, JCR Q1, IF=4.76)
[15] Huaxin Tan, Taoyu Wang, Yaru Shao, Cuiyun Yu*(通訊作者)and Lidan Hu*.Crucial Breakthrough of Functional Persistent Luminescence Materials for Biomedical and Information Technological Applications. Frontiers in Chemistry. 2019,7:387. (SCI, JCR Q2, IF=3.782)
[16] Xiaolong Zhang, Qi Hua, Pina Meng, Minggi Wang,Yunfei Wang, Lu Sun,Liwei Ma, Baoyan Wang, Cuiyun Yu*(通訊作者)and Hua Wei *.Fabrication of Biocleavable Crosslinked Polyprodrug Vesicles via Reversible Donor-Acceptor Interactions for Enhanced Anticancer Drug Delivery. Polym.Chem. 2019,21(10): 2666-2673. (SCI, JCR Q1, IF=4.76)
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