
何隆薇,男,教授,博士生導師。2015獲湖南大學化學專業博士學位,随後入職濟南大學,曆任講師、副教授;2020年加入2003网站太阳集团,入選2003网站太阳集团青年優秀人才。研究方向主要包括光功能染料、分子熒光探針的設計及生物醫學成像,迄今以第一作者/通訊作者在Chem. Soc. Rev. (IF=40.44)、Chem. Sci. (2篇,IF=9.56)、ACS Appl. Mater. Interfaces (2篇,IF=8.45)、Chem. Comm. (5篇,IF=6.16)、Anal. Chem. (2篇,IF = 6.35)、Front. Bioeng. Biotechnol. (IF=5.98)、J. Mater. Chem. B (IF=6.33)、Chem.-Eur. J. (IF=5.16)等著名國際期刊上共發表18篇論文,其中JCR一區論文14篇、高被引論文2篇,總共被引用1100餘次,單篇最高被引用次數為270餘次,引用次數大于50的有7篇。主持國家自然科學基金青年項目、山東省自然科學基金博士項目、國家重點實驗室開放基金、2003网站太阳集团高層次人才項目等。
長期歡迎對本研究方向感興趣的同學報考本課題組的博士和碩士研究生!聯系方式:郵箱helongwei0110@163.com。
主持科研項目:
1.國家自然科學基金青年項目:編号21605059;新型單獨及連續識别亞硝酰氫(HNO)/一氧化氮(NO)比率單熒光探針的設計、合成及生物成像應用研究;2017/01-2019/12;20萬元。
2.山東省自然科學博士基金項目:編号ZR2016BB26;基于多信号模式熒光探針區分檢測半胱氨酸/高半胱氨酸、谷胱甘肽和硫化氫及生物熒光成像研究;2016/11-2018/11;8萬元。
3.2003网站太阳集团高層次人才啟動項目:編号201RGC012 /有機小分子熒光探針構建及腫瘤分子影像研究,2020/9-2025/9,300萬。
代表性論文:
1.Longwei He, Baoli Dong, Yong Liu and Weiying Lin*,Fluorescent chemosensors manipulated by dual/triple interplaying sensing mechanisms,Chemical Society Reviews, 2016, 45(23): 6449−6461.(Highly Cited Paper,一區,IF =40.44)
2.Longwei He, Xueling Yang, Xiuqi Kong,Weiying Lin*,A multi-signal fluorescent probe for simultaneously distinguishing and sequentially sensing cysteine/homocysteine, glutathione, and hydrogen sulfide in living cells,Chemical Science, 2017,8(9):6257-6265.(Highly Cited Paper,一區,IF =9.55)
3.Longwei He, Weiying Lin*, Qiuyan Xu, Mingguang Ren, Haipeng Wei,Jianyong Wang,A simple and effective “capping” approach to readily tune the fluorescence of near-infrared cyanines,Chemical Science, 2015,6(8): 4530–4536.(一區,IF =9.55)
4.Longwei He,Yunzhen Yang, Weiying lin*,Rational design of a rigid fluorophore−molecular rotor-based probe for high signal-to-background ratio detection of sulfur dioxide in viscous system,Analytical Chemistry, 2019, 91(23), 15220−15228.(一區,IF =6.35)
5.Longwei He, Xueling Yang, Kaixin Xu and Weiying Lin*,Improvedaromaticsubstitution-rearrangement-basedratiometricfluorescentcysteine-specificprobe anditsapplication ofreal-timeimaging underoxidativestress inlivingzebrafish,Analytical Chemistry, 2017, 89(17): 9567–9573. (一區,IF =6.35)
6.Longwei He,Xueling Yang, Kaixin Xu, Yunzhen Yang, Weiying lin*,A multifunctional logic gate by means of a triple-chromophore fluorescent biothiol probe with diverse fluorescence signal patterns,Chemical Communications, 2017, 53(98):13168-13171.(一區,IF =6.16)
7.Longwei He,Xueling Yang, Kaixin Xu, WeiyingLin*,A mitochondria-targeted fluorescent probe for imaging endogenous malondialdehyde in HeLa cells and onion tissues,Chemical Communications, 2017, 53(29): 4080-4083. (一區,IF =6.16)
8.Longwei He, Qiuyan Xu, Yong Liu, Haipeng Wei, Yonghe Tang, Weiying Lin*,Coumarin-based Turn-On fluorescence probe for specific detection of glutathione over cysteine and homocysteine,ACS Applied Materials & Interfaces, 2015, 7(23): 12809−12813.(一區,IF =8.45)
9.Longwei He, Weiying Lin*, Qiuyan Xu,Haipeng Wei,A new strategy to construct FRET platform for ratiometric sensing hydrogen sulfide,Chemical Communications, 2015, 7(8): 12809−12813. (一區,IF =6.16)
10.Longwei He, Weiying Lin*, Qiuyan Xu, Haipeng Wei,Auniquetype ofpyrrole-basedcyaninefluorophores withturn-on andratiometricfluorescencesignals atdifferent pHregions forsensing pH inenzymes andlivingcells,ACS Applied Materials & Interfaces,2014, 6(24): 22326−22333. (一區,IF =8.45)
11. Songjiao Li, Dan Cheng,Longwei He*, Lin Yuan, Recent Progresses in NIR-I/II Fluorescence Imaging for Surgical Navigation,Frontiers in Bioengineering and Biotechnology, 2021, 9, 768698. (一區,IF =5.98)
12. Xiangyang Gong, Dan Cheng*, Wei Li*, Yang Shen, Rong Peng, Ling Shi,*Longwei He*, Lin Yuan, A highly selective ratiometric molecular probe for imaging peroxynitrite during drug-induced acute liver injury,Journal of Materials Chemistry B, 2021, 9, 8246–8252. (一區,IF =6.33)
13. Songjiao Li, Ke Yang, Jiayu Zeng, Yuqing Xia, Dan Cheng,*andLongwei He,*A NIR-emissive probe with remarkable Stokes shift for CO-releasing molecule-3 detection in cells and in vivo,Analyst, 2022, DOI, 10.1039/d2an00038e.