一、基本情況
王震，博士，教授、博士生導師，九三學社社員，第十四屆全國人大代表，2003网站太阳集团院長。中組部第十三批“國家海外高層次人才引進計劃”青年項目入選者，湖南省衛生健康高層次人才青年骨幹人才，甘肅省領軍人才，甘肅省傑出青年基金獲得者，甘肅省科技專家庫收錄專家，湖南省藥學會湖湘藥學先鋒獎獲得者，青海省“昆侖英才”項目領軍人才，衡陽市優秀專家，BMC & BMCL雜志青年編委，Organic & Biomolecular Chemistry雜志優秀審稿人，教育部第五輪學科評估專家，科技部“國家外國專家”項目評審專家，創新創業教育先進個人，多次獲得省級研究生畢業論文優秀指導教師和校級本科生優秀論文指導教師稱号，獲得優秀自費留學生獎學金和第95屆日本化學會優秀口頭報告獎，受中央統戰部邀請參加新中國成立70周年閱兵觀禮和中國共産黨成立100周年慶祝活動。2006年6月畢業于蘭州大學化學化工學院，獲得學士學位；2009年9月至2012年7月師從上海有機化學研究所李昂研究員，獲得碩士學位；2012年10月至2015年10月就讀于東京大學2003网站太阳集团，師從Motomu Kanai教授，獲得博士學位。留學期間先後得到Kanai教授的JST-Erato項目助理研究員和日本學術振興會（JSPS）特聘研究員的支持。自獨立工作以來，本着以人為本，為人民健康保駕護航的初心，以新藥發現為目标，以厚植獨特理論基礎的中醫藥作為原創性新化學實體發現的豐富資源和科學依據，緊扣“新藥先導化合物的開發和優化”這一主題，構建了“有機合成新方法促進藥物發現”這條主線，開展天然産物化學、藥物化學、藥物設計和化學生物學研究，圍繞神經退行性疾病、腫瘤、病原微生物感染等重大疾病進行新藥創制研究，建立了基于表型和基于靶标的新藥發現體系，構建了涵蓋分子靶标發現、靶标确認、先導化合物優化、成藥性優化等全面系統的藥物開發模式。開發了多批具有自主知識産權，可規模化生産的具備深入研究價值的候選化合物，有多個化合物正在進行臨床前或臨床研究。已形成以下研究特色與優勢：①聚焦天然活性分子骨架高效構築的合成方法學研究；②緊扣中醫藥振興發展的國家戰略，開展基于吳茱萸堿等傳統中藥活性分子的藥物發現；③基于靶向蛋白降解策略，對“難成藥”靶點進行小分子藥物幹預；④揭示調控線粒體穩态治療神經退行性疾病的全新藥靶及其小分子藥物開發。
到目前為止，王震教授已主持多項科研項目，發現多個具有開發價值的先導化合物，在國際一流期刊上發表科研論文121篇（SCI論文118篇， IF >10：8篇，JCR一區85篇，JCR二區20篇，JCR三區10篇，JCR四區3篇，中文核心2篇，他引2251餘次，單篇最高引223次，H-index為24）及申請專利27項（授權13項，轉讓1項），并參編專著三部/教材一本。兼任全國青年聯合會第十二/十三屆委員、中華醫學會醫學科學研究管理學分會第九屆委員、中國青年科技工作者協會第六屆理事、湖南省九三學社委員、湖南省歐美同學會常務理事、甘肅省青年聯合會第十屆常委、衡陽市九三學社副主委、衡陽市政協委員、九三學社2003网站太阳集团工委主委。
Email: zhenw@usc.edu.cn
二、研究領域
神經退行性疾病、腫瘤、病原微生物感染等重大疾病的新藥創制
三、工作及學習經曆
2024/04-目前 2003网站太阳集团，院長
2021/07-2024/04 2003网站太阳集团衡陽醫學院，副院長（正處級）
2020/04-2024/04 2003网站太阳集团衡陽醫學院2003网站太阳集团，教授
2015/09-2020/04 國家海外高層次人才引進計劃青年項目入選者，蘭州大學2003网站太阳集团/蘭州大學化學化工學院功能有機分子化學國家重點實驗室，教授，博士生導師
2015/04-2015/10 JSPS（日本學術振興會），特聘研究員（DC2）
2013/04-2015/03 東京大學（Motomu Kanai實驗室），助理研究員
2012/07-2012/10 上海有機化學研究所氟化學重點實驗室（張新剛實驗室），助理研究員
2007/08-2008/07 百靈威技術有限公司，助理研究員
2006/07-2007/06 江蘇豪森藥業有限公司，助理研究員
2012/10-2015/09 東京大學2003网站太阳集团，博士
2009/09-2012/07 中國科學研究院上海有機化學研究所，碩士
2002/09-2006/07 蘭州大學化學化工學院，學士
四、社會兼職
中華醫學會醫學科學研究管理學分會第九屆委員
2003网站太阳集团附屬第一醫院兼職教授
湖南省藥學會第15屆理事
蘭州市第二人民醫院外聘專家
中國科學院藏藥研究重點實驗室客座研究員
中國科學院近代物理研究所客座研究員
五、教學工作
從事藥物化學課程本科課程，指導學生開展的各類創新創業項目主要包括：甘肅省“挑戰者杯”1項（省三等獎），蘭州大學“挑戰杯”項目2項（分别獲得二等獎和三等獎），“國創”項目3項（一項結題被評為優秀，兩項中期答辯被評為優秀），“校創”項目4項（兩項結題被評為校優秀），“萃英創新基金”1項，化工院創新項目1項，已發表SCI論文多篇，通過這些項目的開展，培養了一批熱愛科研的優秀學生，其中兩人申請到世界知名學府日本理化技術研究所的侯召明課題組繼續深造和一人已申請到北海道大學繼續攻讀研究生，其餘學生大部分參加了我校的“優培計劃”或者保送研究生，繼續在王震課題組攻讀研究生，為我院選留優秀學生做出積極的努力。王震教授獲得2017年“挑戰杯”蘭州大學大學生課外學術科技作品優秀指導教師、2016年蘭州大學學生創新創業行動計劃優秀指導教師和蘭州大學2016-2017學年創新創業教育先進個人的稱号。
教改課題：地方高校藥學專業研究生“築夢+逐夢”式國際化人才培養模式的探索與實踐（重點項目，5.0萬元）；湖南省普通高等學校教學改革研究：藥學類專業大學生創新創業教育的發展模式研究（普通教育 重點項目，HNJG-20230580）3.0萬元。
六、承擔課題
1. 湖南省衛生健康高層次人才重大科研專項：MTDls導向的新型抗AD藥物發現及其作用機制研究 （2023.10.31-2027.10.30, 20230410）
2. 湖南省面上基金項目：基于合并法多靶點配體藥物設計策略的新型抗AD藥物分子的發現 （2023.01.01-2025.12.31，2023JJ30527）
3. 青海省“昆侖英才·高端創新創業人才”項目領軍人才項目：（2024.01.01-2026.12.31）湖南省衛生健康高層次人才青年骨幹人才項目（2022.05-2027.05）
4. 甘肅省傑出青年基金項目：Lycoplanine A的全合成及抗帕金森病活性研究(2020.11.01-2023.10.31, 20JR5RA304)
5. 蘭州市科技發展計劃項目——新冠肺炎防控技術研究項目：一種治療新冠肺炎藥物的研發（2020.04-2022.04, 2020-XG-34）
6. 青海省重點研發與轉化計劃項目：藏藥角茴香中抗炎藥物候選分子的結構優化與新藥臨床前研究 (202002040061, 2020.01.01-2022.12.31)
7. 甘肅省極端環境微生物資源與工程重點實驗室開放基金項目：深海天然産物Chrysamide B衍生物的設計合成及其抗胃癌活性和作用機制研究 (2020.01.01-2021.12.31)
8. “中央高校基本科研業務費專項資金”科研創新團隊建設項目：新型含硫藥物的設計合成與抗炎/抗腫瘤活性評價(2019.01.01-2020.12.30, lzujbky-2019-ct08)
9. 青海省自然科學基金面上項目：藏藥尼泊爾黃堇抗胃潰瘍機制及活性單體的分離合成研究 (2019.01.01-2021.12.31, 2019-ZJ-907)
10. 青海省院藏藥研究重點實驗室開放課題：細果角茴香活性成分合成及修飾改造(2018.11.01-2019.11.01)
11. 國家海外高層次人才引進計劃青年項目 (2017-2020)
12. 中央高校基本科研業務費：金屬钯催化的碳氫鍵活化和環氧乙烷類化合物的偶聯新反應開發和應用 (2016.01.01-2017.06.30, lzujbky-2016-153)
13. 甘肅省留學人員科技活動擇優資助項目：具有抗癌活性的Duocarmycin家族天然産物的全合成研究 (2016.10.09-2017.06.30, 20161228)
14. 蘭州大學科研啟動經費項目
七、代表性文章
1) Wang, Z. (第一作者); Ni, J. Z.; Kuninobu, Y.* and Kanai, M.* “Copper-Catalyzed Intramolecular C(sp3)-H and C(sp2)-H Amidation by Oxidative Cyclization” Angew. Chem. Int. Edit. 2014, 53, 3496；Angew. Chem. 2014，126，3564； [highlighted in Synfacts 2014, 10, 0570].
2) Wang, Z. (第一作者); Kuninobu, Y.* and Kanai, M.* “Palladium-Catalyzed Oxirane-Opening Reaction with Arenes via C-H Bond Activation” J. Am. Chem. Soc. 2015, 137, 6140. [JACS Most Read top 5 Articles in May and June, 2015].
3) Bian, M.;# Wang, Z.;# (共同第一作者) Xiong, X. C.; Sun, Y.; Matera, C.; Nicolaou, K. C.* and Li, A.* “Total Syntheses of Anominine and Tubingensin A” J. Am. Chem. Soc. 2012, 134, 8078. [JACS Most Read Articles in 12 months (Aug. 2011-July 2012); highlighted in Synfacts 2012, 8, 814 and Organic Chemistry Portal].
4) Wang, H. H.;# Wang, X. D.;# Yin, G. F.; Zeng, Y. F.; Chen, J. J.* and Wang, Z.* (通訊作者) “Recent Advances in Transition-Metal-Catalyzed C-H Alkylation with Three-Membered Rings” ACS Catal. 2022, 12, 2330.
5) Yang, Y. H.;# Gao, W. W.;# Wang, Y. Q.; Wang, X. D.; Cao, F.; Shi, T.* and Wang, Z.* (通訊作者) “Recent Advances in Copper Promoted Inert C(sp3)-H Functionalization.” ACS Catal. 2021, 11, 967.
6) Wang, Y. Q.;# Deng, J. D.;# Chen, J. H.; Cao, F.; Hou, Y. S.; Yang, Y. H.; Deng, X. M.; Yang, J. R.; Wu, L. X.; Shao, X. F.; Shi, T.* and Wang, Z.* (通訊作者) “Dechalcogenization of Aryl Dichalcogenides to Synthesize Aryl Chalcogenides via Copper Catalysis” ACS Catal. 2020, 10, 2707.
7) Zou, J. X.;# Chen, J. H.;# Shi, T.;#, * Hou, Y. S.; Cao, F.; Wang, Y. Q.; Wang, X. D.; Jia, Z.; Zhao, Q. Y. and Wang, Z.* (通訊作者) “Phthalimide-Carried Disulfur Transfer to Synthesize Unsymmetrical Disulfanes via Copper Catalysis” ACS Catal. 2019, 9, 11426.
8) Li, J. F.;# Wang, X. D.;# Zhang, H. H.; Hu, X. L.; Peng, X.; Jiang, W. F.; Zhuo, L. S.; Peng, Y.; Zeng, G.; Wang, Z. (通訊作者) “Fenamates: Forgotten treasure for cancer treatment and prevention: Mechanisms of action, structural modification, and bright future” Med. Res. Rev. 2024, 1.
9) He, C. Y.; Wang, Z.; Wu, C. Z.; Qing, F. L. and Zhang, X. G.* “Pd-Catalyzed Oxidative Cross-Coupling between Two Electron Rich Heteroarenes” Chem. Sci. 2013, 4, 3508.
10) Jian, L.; # Chen, J. J.;# Hu, Q. L.; Wang, Z.* (通訊作者) and Xiong, X. F. * “Recent progress of chemical methods for lysine site-selective modification of peptides and proteins” Chin. Chem. Lett. 2024, 6, 110126.
11) Li, J. F. #; Hu, X. L. #; Zhang, H. H.; Peng, Y.; Li, S.; Xiong, Y. X.; Jiang, W. F.* and Wang, Z.* (通訊作者) “N-2-(Phenylamino) Benzamide Derivatives as Dual Inhibitors of COX-2 and Topo I Deter Gastrointestinal Cancers via Targeting Inflammation and Tumor Progression” J. Med. Chem. 2022, 65, 10481.
12) Lei, F.;# Xiong, Y. X.;# Wang, Y. Q.; Zhang, H. H.; Liang, Z. Y.; Li, J. F.; Feng, Y. Y.; Hao, X. Y.* and Wang, Z.* (通訊作者) “Design, Synthesis, and Biological Evaluation of Novel Evodiamine Derivatives as Potential Antihepatocellular Carcinoma Agents” J. Med. Chem. 2022, 65, 7975.
13) Wei, X. Z.;# Zhang, X.;# Peng, Y.; Wu, J, B.; Mo, H. X.; An, Z. G.; Deng, X. Y.; Peng, Y.; Liu, L. Y.; Jiang, W. F.; Chen, J. J.; Hu, Z. C.;* Wang, Z.* and Zhuo, L. S.* “Identification of a Novel 10-hydroxyevodiamine Prodrug as a Potent Topoisomerase Inhibitor with Improved Aqueous Solubility for Treatment of Hepatocellular Carcinoma.” Eur. J. Med. Chem. 2024, 279, 116807.
14) Wu, G. P.;# Li, B.;# Wei, X. Z.; Chen, Y. X.; Zhao, Y. T.; Peng, Y.; Su, J. H.; Hu, Z. C.; Zhuo, L. S.; Tian, Y.;* Wang, Z.* (通訊作者) and Peng, X.* “Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke” Eur. J. Med. Chem. 2024, 278, 116795.
15) Long, L.;# Xu, J. C.;# Qi, X. W.;# Pen, Y.; Wang, C. K.; Jiang, W. F.; Peng, X.; Hu, Z. C.; Yi, W. J.; Xie, L. M.; Lei, X. Y.; Wang, Z.* (通訊作者) and Zhuo, L. S.*“Discovery of novel small molecules targeting the USP21/JAK2/STAT3 axis for the treatment of triple-negative breast cancer” Eur. J. Med. Chem. 2024, 273, 116500.
16) Wang, Y. Q.; # Long, L.; # Zhuo, L. S.; Zhang, H. H.; Luo, T.; Deng, J. D.; Wang, Y. Y.; Li, Z.; Wang, Z.* (通訊作者) and Peng, X.* “Design, Synthesis, and Biological Evaluation of 1-styrenyl Isoquinoline Derivatives for Anti-hepatocellular Carcinoma Activity and Effect on Mitochondria” Eur. J. Med. Chem. 2023, 256, 115420.
17) Deng, J. D#; Long, L. #; Peng, X.; Jiang, W. F.; Peng, Y.; Zhang, X.; Zhao, Y. T.; Tian, Y.; Wang, Z.* and Zhuo, L. S.* “N(14)-substituted evodiamine derivatives as dual topoisomerase 1/tubulin-Inhibiting anti-gastrointestinal tumor agents” Eur. J. Med. Chem. 2023, 255, 115366.
18) Wang, Z. #,* (共同第一作者，通訊作者); Xiong, Y. X.;# Peng, Y.; Zhang, X.; Li, S.; Peng, Y.; Peng, X.; Zhuo, L. S.* and Jiang, W. F.* “Natural product evodiamine-inspired medicinal chemistry: Anticancer activity, structural optimization and structure-activity relationship” Eur. J. Med. Chem. 2023, 247, 115031.
19) Zhang, H. H.;# Peng, Y.;# Zhuo, L. S.; Wang, Y. Y.; Zeng, G.; Wang, S. Z.; Long, L.; Li, X. L.* and Wang, Z.* (通訊作者) “Recent Advance on Pleiotropic Cholinesterase Inhibitors Bearing Amyloid Modulation Efficacy” Eur. J. Med. Chem. 2022, 242, 114695.
20) Zhang, H. H.;# Wang, Y. Y.;# Wang, Y. Q.; Li, X. L.;* Wang, S. Z.* and Wang, Z.* (通訊作者) “Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease” Eur. J. Med. Chem. 2022, 240, 114606.
21) Hu, X. L.; # Li, J. F.; # Zhang, H. H.; Yu, Q. W.; Wang, Y. Y.; Li, X. L.; Long, L.; Jiang, W. F. * and Wang, Z.* (通訊作者) “Discovery of Dual Inhibitors of Topoisomerase I and Cyclooxygenase-2 for Colon Cancer Therapy” Eur. J. Med. Chem. 2022, 240, 114560.
22) Liang, Z. Y.;# Wang, Y. Q.;# Zhang, H. H.; Deng, J. D.; Lei, F.; Li, J. F.; Shi, T.; Wang, S. Z.;* Li, R. H.* and Wang, Z.* (通訊作者) “Design, synthesis and bioactivity evaluation of favorable evodiamine derivative scaffold for developing cancer therapy” Eur. J. Med. Chem. 2022, 239, 114530,
23) Deng, X. M.;# Luo, T.;# Zhang, X.; Li, Y. H.; Xie, L. M.; Jiang, W. F.; Liu, L. Y.* and Wang, Z.* (通訊作者) “Design, Synthesis and Biological Evaluation of 3-Arylisoquinoline Derivatives as Topoisomerase I and II Dual Inhibitors for the Therapy of Liver Cancer” Eur. J. Med. Chem. 2022, 237, 114376.
24) Liu, D.;# Zhang, H. H.;# Wang, Y. Y.; Liu, W. C.; Yin, G. F.; Wang, D. G.; Li, J. F.; Shi, T. and Wang, Z.* (通訊作者) “Design, Synthesis, and Biological Evaluation of Carbamate Derivatives of N-salicyloyl Tryptamine as Multifunctional Agents for the Treatment of Alzheimer's Disease” Eur. J. Med. Chem. 2022, 229, 114044.
25) Deng, X. M.;# Luo, T.;# Li, Z.;# Wen, H. X.; Zhang, H. H.; Yang, X. Y.; Lei, F.; Liu, D.; Shi, T.; Zhao, Q. Y. and Wang, Z.* (通訊作者) “Design, Synthesis and Anti-Hepatocellular Carcinoma Activity of 3-Arylisoquinoline Alkaloids” Eur. J. Med. Chem. 2022, 228, 113985.
26) Liang, Z. Y.;# Lei, F.;# Deng, J. D.; Zhang, H. H.; Wang, Y. Q.; Li, J. F.; Shi, T.; Yang, X. Y.* and Wang, Z.* (通訊作者) “Design, Synthesis and Bioactivity Evaluation of Novel Evodiamine Derivatives with Excellent Potency against Gastric Cancer” Eur. J. Med. Chem. 2022, 228, 113960.
27) Lu, Y. M.;# Feng, Y. Y.;# Li, Z.; Li, J. F.; Zhang, H. H.; Hu, X. L.; Jiang, W. F.; Shi, T. and Wang, Z.* (通訊作者) “Novel Piperazine Based Benzamide Derivatives as Potential Anti-Glioblastoma Agents Inhibiting Cell Proliferation and Cell Cycle Progression” Eur. J. Med. Chem. 2022, 227, 113908.
28) Feng, Y. Y.;# Lu, Y. M.;# Li, J. F.;# Zhang, H. H.; Li, Z.; Feng, H. Z.; Deng, X. M.; Liu, D.; Shi, T.; Jiang, W. F.; He, Y. X.;* Zhang, J.* and Wang, Z.* (通訊作者) “Design, Synthesis and Biological Evaluation of Novel o-Aminobenzamide Derivatives as Potential Anti-Gastric Cancer Agents in Vitro and in Vivo” Eur. J. Med. Chem. 2022, 227, 113888.
29) Li, J. F.;# Hu, X. L.;# Luo, T.; Lu, Y. M.; Feng, Y. Y.; Zhang, H. H.; Liu, D.; Fan, X. H.; Wang, Y. Q.; Jiang, L. M.; Wang, Y. Y.; Hao, X. Y.; Shi, T.* and Wang, Z.* (通訊作者) “N-2-(phenylamino) Benzamide Derivatives as Novel Anti-Glioblastoma Agents: Synthesis and Biological Evaluation” Eur. J. Med. Chem. 2021, 226, 113817.
30) Fan, X. H.;# Li, J. F.;# Long, L.;# Shi, T.;* Liu, D.; Tan, W.; Zhang, H. H.; Wu, X. Y.; Lei, X. Y.* and Wang, Z.* (通訊作者) “Design, Synthesis and Biological Evaluation of N-anthraniloyl Tryptamine Derivatives as Pleiotropic Molecules for the Therapy of Malignant Glioma” Eur. J. Med. Chem. 2021, 222, 113564.
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108) Liang, Y.; Li, S. W.; Song, X. D.; Zhou, D. S.; Zhi, D. J.; Hao, B. C.; Liu, Y.; Liang, J. P. and Wang, Z.* (通訊作者) “Swainsonine Producing Performance of Alternaria Oxytropis was improved by Heavy-Ion Mutagenesis Technology” FEMS Microbiol. Lett. 2021, 368, fnab047.
109) Zhang, T. F.; Du, S. B.; Wang, Y.; Guo, Y. Z.; Yi, Y. M.; Liu, B.;* Liu, Y.;* Chen, X. M.;* Zhao, Q. Y.; He, D.; Wang, Z.; Zhang, H. and Ma, Q. L. “Novel Carborane Compounds Based on Cyclooxygenase-2 Inhibitors for Effective Boron Neutron Capture Therapy of Tongue Squamous Cell Carcinoma” ChemistrySelect. 2020, 5, 14652.
110) Wang, X. D.;# Wang, H. H.;# Wu, X.;# Yu, T. Q.; Gao, W. W.; Shi, T.; Peng, X.; He, D.* and Wang, Z.* (通訊作者) “Total Synthesis of (+)-Mintlactone and (–)-Isomintlactone via SmI2-Induced Radical Cyclization” Synlett. 2017, 28,1660.
111) Wang, Z. (第一作者); Kuninobu, Y.* and Kanai, M.* “Molybdenum-Mediated Desulfurization of Thiols and Disulfides” Synlett. 2014, 25, 1869.
112) Liu, S. Z.; Li, J.; Xue, C. G.; Xu, X. T.;* Lei, L. S.; Huo, C. Y.; Wang, Z. and Wang, S. H.;* “Copper-Promoted Cyanation of Aryl Iodides with N,N-Dimethyl Aminomalononitrile” Tetrahedron Lett. 2021, 65, 152749.
113) Yu, T. Q.;# Hou, Y. S.;# Jiang, Y.;# Xu, W. X.;# Shi, T.; Wu, X.; Zhang, J. C.; He, D.* and Wang, Z.* (通訊作者) “KBr-Catalyzed N-S Bond Formation via Oxidative Dehydrogenation” Tetrahedron Lett. 2017, 58, 2084.
114) Luo, T.;# Deng, X. M.;# Li, Z.; Liu, D.; Weng, X.; and Wang, Z.* (通訊作者) “Synthesis and anti-hepatocellular carcinoma effects of corydamine from Hypecoum Leptocarpum” Photochem. Lett. 2022, 51, 119.
115) Liu, S. Z.; Cui, M. Y.; Wang, B. W.; Hu, C. M.; Zheng, Y. Y.; Li, J.; Xu, X. T.;* Wang, Z. and Wang, S. H.* “Triethyl Amine-Promoted Cyclization Reaction between Cyclopropenone and alpha-Halogenated Hydroxamate for the Synthesis of Polysubstituted 6H-1,3-Oxazin-6-one” Chin. J. Org. Chem. 2021, 41, 1622.
116) Duan, X. Y.; Liu, X. F.; Dong, Y.; Yang, J.; Zhang, J.; He, S. J.; Yang, F. T.; Wang, Z. and Dong, Y. M.* “A Green HPLC Method for Determination of Nine Sulfonamides in Milk and Beef, and Its Greenness Assessment with Analytical Eco-Scale and Greenness Profile” J. AOAC Int. 2020, 103, 1181.
117) Hu, C. H.; Wei, D. D.; Sun, X. F.; Lin, R. L.; Hu, M. M.; Tang, L.; Wang, Z.; He, D.; “Synthesis, Crystal Structure, Antitumor Activities and Docking Study of 1-(2-(1H-Indol-3-yl)ethyl) -3-(2-methoxyphenyl)urea” Chin. J. Struct. Chem. 2018, 37, 393.
118) Yang, F. T.; Du, X. Y.; Wang, Z. and Dong, Y. M.* “A Gas Chromatography Flame Ionization Detector Method for Rapid Simultaneous Separation and Determination of Six Active Ingredients of Anticold Drug” Curr. Pharm. Anal. 2022, 18, 71.
119) Shi, T. #; Yin, G. F. #; Wang, X. D.; Xiong, Y. X.; Peng, Y.; Li, S.; Zeng, Y. F. *; Wang, Z.* (通訊作者) “Recent advances in the syntheses of pyrroles” Green Synth. Catal. 2022, 4, 20
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121) 梁妍, 宋向東, 謝宗秀, 劉宇, 郝寶成, 王震, 王保海*, 梁劍平; 瘋草内生真菌研究進展; 動物醫學進展，2020, 41, 106.
八、申請發明專利
1. 王震，譚雯，李俊芳，鄧傑丹，張紅花. 一種吳茱萸生物堿衍生物及其合成方法和應用：中國，ZL201910085249.X [P]. 2021-06-29. 授權-高價值發明專利
2. 王震，張紅花，鄧傑丹，梁妍，石桃，李俊芳. 一種吳茱萸堿衍生物在制備治療淺表真菌感染藥物中的應用：中國，ZL202111134080.6 [P]. 2023-04-14. 授權
3. 王震，劉林義，李博，彭穎，曾要富，彭雪，陳勁進，王姝之，卓林勝，李霜，彭豔，熊永霞. 一種吳茱萸堿衍生物的制備方法，中國，ZL202210997815.6 [P]. 2024-08-13. 授權
4. 王震，張紅花，劉丹，王玉英，李俊芳，石桃. 一種苯甲酸色胺衍生物及其制備與應用：中國，ZL202110856721.2 [P]. 2023-07-07. 授權
5. 王震，張紅花，劉丹，石桃，王玉英，李俊芳. 一種氨基甲酸酯類鄰氨基苯甲酸色胺衍生物及其制備與應用：中國，ZL202110798096.0 [P]. 2023-03-14. 授權
6. 王震，範曉紅，石桃，李俊芳，胡曉玲. 一種色胺水楊酸類化合物及其制備和應用：中國，ZL202011093086.9 [P]. 2024-03-19. 授權
7. 王震，謝黎明，胡曉玲，張茜，石桃，李俊芳，彭燕，王雨晴，王玉英. 一種托滅酸類衍生物及其制備與應用：中國，ZL202210341962.8 [P]. 2024-06-14. 授權
8. 王震，石桃，馮益悅，盧瑩美，李俊芳，張紅花. 一種含叔胺的鄰氨基苯甲酰胺類化合物及其制備與應用：中國，ZL202110382738.9 [P]. 2022-07-19. 授權
9. 王震，石桃，張紅花，盧瑩美，馮益悅，李俊芳. 一種基于恩替諾特骨架的鄰氨基苯甲酰胺類化合物及其制備與應用：中國，ZL202110382954.3 [P]. 2022-07-05. 授權
10. 王震，石桃，李俊芳，張紅花，盧瑩美，馮益悅. 一種基于伏立諾他骨架的鄰氨基苯甲酰胺類化合物及其制備與應用：中國，ZL202110382959.6 [P]. 2023-01-06. 授權
11. 王震，朱龍青，範曉紅，李俊芳，石桃，張紅花，唐愛民。一種具有抗腫瘤活性的chrysamides B衍生物及其制備和應用：ZL202010188913.6 [P]. 2022-08-30. 授權
12. 王震，陳金鴻，彭雪，侯永勝，鄧傑丹. 含硝基天然産物chrysamides B合成方法及其非對映異構體-化合物：中國，ZL201810669903.7 [P]. 2021-08-24. 授權
13. 王震，謝黎明，張茜，李昭，馮益悅，盧瑩美. 一種1-苯乙烯基異喹啉衍生物及其制備與應用，中國，ZL202210026209.X [P]. 2024-04-17. 授權
14. 王震，賀春陽，曾要富，江偉凡，李學林，龍鱗，一種氟芳烴氨基酸及其合成方法：中國，ZL202111472717.2 [P]. 2023-06-23. 授權
15. 王震，石桃，朱龍青，李俊芳，範曉紅，張紅花，馮益悅，盧瑩美，王曉東，唐愛民. 一種新型哌嗪類化合物及其制備方法和應用：中國，ZL201911297009.2 [P]. 2023-5-26. 授權
16. 王震，劉林義，鄧雪梅，羅添，張茜，李躍華，謝黎明，江偉凡. 一種3-芳基異喹啉衍生物及其制備與應用，中國，CN202210158124.7 [P]. 2023-08-22. 授權
17. 梁劍平，劉宇，王震，梁妍，郝寶成，王學紅，郭文柱，趙鳳舞，楊珍，賈忠，張新剛，陳虹. 一種甘草次酸酯及其制備方法和在制備抗病毒藥物中的應用：中國，ZL201810205157.6 [P]. 2019-12-31. 授權-權力轉移
18. 王震，彭穎，廖紅伍，曾國，周玉生，張茜，孫守元，江金環，江偉凡，劉林義，陳勁進，卓林勝，米靜，李博，李志毅. 一種吳茱萸堿衍生物抗淺部真菌乳膏的制備方法，中國，CN202211163250.8 [P]. 2022-09-23. 實質審查
19. 王震，彭穎，曾國，廖紅伍，米靜，張茜，趙貴全，江偉凡，卓林勝，劉林義，陳勁進，李國華，龍靈馨，李志毅. 一種吳茱萸堿衍生物抗淺部真菌固體脂質納米粒凝膠的制備方法，中國，CN202211163538.5 [P]. 2022-09-23. 實質審查
20. 王震，陳勁進，李霜，江偉凡，劉林義，李博，曾要富，彭雪，王姝之，卓林勝，熊永霞，彭豔. 一種鄰吡咯烷基苯甲酰胺類化合物的制備方法. 中國，CN202211450418.3. 實質審查
21. 王震，石桃，範曉紅，李俊芳. 一種新型色胺衍生物及其制備方法和應用：中國，CN201911145064.X [P]. 2019-11-12. 實質審查
22. 王震，侯永勝，範曉紅，李俊芳，鄧傑丹. 一種1，3-苯并噻嗪酮類化合物及其合成方法和應用：中國，CN201811319974.0 [P]. 2018-11-07. 實質審查
23. 王震，彭雪，王姝之，卓林勝，江偉凡，陳勁進，趙雨婷，巫根平，曹柳麗，吳坤，趙亞蓉，曾晶. 一種 N-乙酰色胺類化合物、組合物和應用：中國，CN202310876756.1實質審查
24. 王震，卓林勝，江偉凡，彭雪，陳勁進，曾要富，王姝之，劉林義，張宇，陳淑婷，韋秀珍，李博. 一種水溶性吳茱萸堿衍生物和應用：中國，CN202311104152.1實質審查
25. 王震，江偉凡，彭雪，陳勁進，卓林勝，王姝之，曾要富，劉林義，張宇，韋秀珍，李博，陳淑婷. 一種含酯基取代吳茱萸堿衍生物、制備方法和應用：中國CN202311104165.9實質審查
26. 王震，石桃，李俊芳，張紅花，王曉東. 一種N-芳基鄰氨基苯甲酰胺類化合物及其制備和應用：中國，CN202110311265.3 [P]. 2021-03-24. 實質審查
27. 王震，張紅花，鄧傑丹，梁子怡，雷芳，石桃. 一種吳茱萸堿衍生物及其制備和應用：中國，CN202111133320.0 [P]. 2021-09-27. 實質審查
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