一、基本情況
李宋嬌，分析化學博士；校聘教授，碩士生導師。主要研究方向為分子熒光探針設計及生物醫學成像應用研究。以第一作者或通訊作者在Analytical Chemistry、ACS Sensors、Chemical Communications、Sensors and Actuators B: Chemical等專業期刊上發表SCI收錄論文10餘篇。主持國家自然科學基金青年基金、湖南省自然科學基金青年基金、湖南省教育廳優秀青年基金、2003网站太阳集团博士啟動基金等多個科研項目。參與國家自然科學基金面上項目2項。
Email:lisongjiao@usc.edu.cn；QQ：1533974815
二、研究領域
1. 近紅外分子熒光探針的合成及活體成像分析。
2.疾病相關診斷及治療。
三、工作及學習經曆
2021/9-至今，2003网站太阳集团，2003网站太阳集团，校聘教授
四、教學工作
目前承擔課程：無機化學B、化學原理等。
五、承擔課題
1.國家自然科學基金青年基金，雙靶向-雙鎖型近紅外熒光探針的構建及其在腦膠質瘤精準成像中的應用（22304074），2024.1-2026.12，30萬，在研，主持；
2. 湖南省青年基金項目，可激活靶向性近紅外熒光探針的構建及在腦膠質瘤成像中的應用研究（2022JJ40358），2022.1-2024.12，5萬元，在研，主持；
3. 湖南省教育廳優秀青年項目，近紅外熒光探針的構建及其在癫痫疾病成像中的應用研究（22B0403），2023.1-2025.12，6萬元，在研，主持。
4. 2003网站太阳集团博士科研啟動基金，可激活靶向性近紅外熒光探針的構建及在腦膠質瘤成像中的應用研究，2022-2024，30萬，在研，主持；
六、代表性文章
1) Songjiao Li, Peipei Wang, Miantai Ye, Ke Yang, Dan Cheng, Zhiqiang Mao, Longwei He, Zhihong Liu,A cysteine-activatable near-infrared fluorescent probe for dual-channel tracking lipid droplets and mitochondria in epilepsy, Analytical Chemistry，2023, 95, 11, 5133.(中科院一區Top，IF = 6.7)
2) Li, Songjiao; Song, Dan; Huang, Weijing; Li, Zhen; Liu, Zhihong ; In Situ Imaging of Cysteine in the Brains of Mice with Epilepsy by a Near-Infrared Emissive Fluorescent Probe, Analytical Chemistry, 2020, 92(3): 2802-2808. (中科院一區Top，IF = 6.7)
3)Li, Songjiao; Li, Yong-Fei; Liu, Hong-Wen; Zhou, Dong-Ye; Jiang, Wen-Li; Juan Ou-Yang; Li, Chun-Yan ; A Dual-Response Fluorescent Probe for the Detection of Viscosity and H2S and Its Application in Studying Their Cross-Talk Influence in Mitochondria, Analytical Chemistry, 2018, 90(15): 9418-9425. (中科院一區Top，IF = 6.7)
4)Li, Songjiao; Li, Chun-Yan; Li, Yong-Fei; Fei, Jun-Jie; Wu, Ping; Yang, Bing; Ou-Yang, Juan; Nie, Shi-Xin ; Facile and Sensitive Near-Infrared Fluorescence Probe for the Detection of Endogenous Alkaline Phosphatase Activity In Vivo, Analytical Chemistry, 2017, 89(12): 6854-6860. (中科院一區Top，IF = 6.7)
5) Li, Songjiao; Zhou, Dong-Ye; Li, Yongfei; Liu, Hong-Wen; Wu, Ping; Ou-Yang, Juan; Jiang, Wen-Li; Li, Chun-Yan ; Efficient Two-Photon Fluorescent Probe for Imaging of Nitric Oxide during Endoplasmic Reticulum Stress, ACS Sensors, 2018, 3, 2311 (中科院一區Top，IF = 8.2)
6) Peipei Wang, Ying Liu, Liang Tao, Dan Cheng, Longwei He, Songjiao Li*. Monitoring cysteine changes and assessing ferroptosis in diabetic mice with a lysosome-targeted near-infrared fluorescence probe. Sensors and Actuators B: Chemical, 2024,421,136549.（JCR1區，IF：8.0）
7) Songjiao Li, Ke Yang, Peipei Wang, Ying Liu, Dan Cheng, Longwei He.Monitoring heat stroke with a HClO-activatable near-infrared fluorescent probe. Sensors and Actuators B: Chemical 2023,385,133696.（JCR1區，IF：8.0）
8)Songjiao Li;Ke Yang;Ying Liu;Peipei Wang;Dan Cheng;Longwei He; An endoplasmic reticulum-targeted near-infrared probe for monitoring HClO fluctuation in diabetic mice and human blood, Sensors and Actuators B: Chemical, 2022, 379, 133253.（JCR1區，IF：8.0）
9) Ying Liu, Min Deng, Peipei Wang , Yin Liu ,Songjiao Li*, Longwei He.Visualizing lysosomes hypochlorous acid in Parkinson’s disease models by a novel fluorescent probe.Talanta,2024,279,126635.（JCR1區，IF：5.6）
10) Peipei Wang, Siwei Ai, Min Deng, Ying Liu, Yin Liu, Longwei He,Songjiao Li*. A lysosomal-targeted and viscosity-ultrasensitive near-infrared fluorescent probe for sensing viscosity in cells and a diabetic mice model.Talanta2024,278,126506.（JCR1區，IF：5.6）
11) Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng,Songjiao Li, Longwei He. Imaging peroxynitrite in endoplasmic reticulum stress and acute lung injury with a near-infrared fluorescent probe.Analytica Chimica Acta2024,1286,342050.（JCR1區，IF：5.7）
12) Songjiao Li, Peipei Wang, Ke Yang, Ying Liu, Dan Cheng, Longwei He, Construction of HClO activated near-infrared fluorescent probe for imaging hepatocellular carcinoma.Analytica Chimica Acta2023,1252,341009.（JCR1區，IF：5.7,高被引論文）
13)Songjiao Li,Peipei Wang, Wenqi Feng, Yunhui Xiang, Kun Dou, Zhihong Liu, Simultaneous imaging of mitochondrial viscosity and hydrogen peroxide in Alzheimer's disease by a single near-infrared fluorescent probe with a large Stokes shift, Chemical communications, 2020, 56, 1050.（JCR1區，IF：6.065）