一、基本情況
江金環，中藥學博士；講師，碩士生導師。主要從事小分子藥物抗腫瘤、抗炎等研究。參與國家自然科學基金面上項目1項，主持湖南省自然科學基金青年項目、湖南省教育廳一般項目、衡陽市科技廳指導項目、2003网站太阳集团博士啟動金項目等多項科研項目。近年來，以第一或通訊作者發表SCI學術論文10餘篇，其中高被引論文1篇，參與作者論文多篇。
Email: jjhuan1116@163.com
二、研究領域
1.小分子藥物抗腫瘤、抗炎等機制研究
2.靶向修飾納米粒作為藥物傳遞系統的研究
三、工作及學習經曆
2019/5-至今，2003网站太阳集团，2003网站太阳集团，講師
2015/9-2019/2，澳門科技大學，中醫2003网站太阳集团 博士
四、社會兼職
中國藥理學會教學與科普專業委員會青年委員
Frontiers in Bioengineering and Biotechnology，Frontiers in pharmacology等雜志客座編輯。
五、教學工作
主講藥理學、機能實驗學、臨床藥物治療學等課程。主持2003网站太阳集团教學改革研究重點項目、船山學院教學改革研究一般項目等，以第一作者發表教學改革論文3篇。
六、承擔課題
1. 湖南省自然科學基金：2021JJ40474，主持，2021/01-2023/12
2. 湖南省教育廳科學研究項目：20C1602，主持，2020/09-2023/06
3. 2003网站太阳集团博士啟動基金：190XQD141，主持
4. 2003网站太阳集团教學與改革研究項目：2022ZD-XJG08, 2020ZD-XJG14，主持
七、代表性文章
(1)Shiying Ye; Xiangyan Hu; Shaowei Sun; Bo Su; Jiye Cai; Jinhuan Jiang*,Oridonin promotes RSL3-induced ferroptosis in breast cancer cells by regulating the oxidative stress signaling pathway JNK/Nrf2/HO-1.European Journal of Pharmacology.2024,974(17620),1-12.
(2) Xiangyan Hu, Sisi Huang, Shiying Ye, Jinhuan Jiang*,The Natural Product Oridonin as an Anticancer Agent: Current Achievements and Problems,Current Pharmaceutical Biotechnology, 2024,25(6),655-664.
(3) Shiying Ye; Yi Gao;Xiangyan Hu; Jiye Cai; Shaowei Sun; Jinhuan Jiang*.Research progress and future development potential of Flammulina velutipes polysaccharides in the preparation process, structure analysis, biology, and pharmacology: A review.Int J Biol Macromol. 2024 May;267(Pt 1):131467.
(4) Shiying Ye; Shaowei Sun; Jiye Cai;Jinhuan Jiang* Advances in the Synthesis and Bioactivity of Polysaccharide Selenium Nanoparticles: A Review.Mini Rev Med Chem. 2024;24(16):1535-1554.
(5) Ye, Shi Ying; Sun, Shao Wei; Cai, Ji Ye; Jiang, Jin Huan*, Research progress and future
development potential of oridonin in pharmacological activities, Current Molecular Pharmacology ,2022.
(6)Jinhuan Jiang, Jiang Pi, Jiye Cai. Oridonin exhibits anti-angiogenic activity in human umbilical vein endothelial cells by inhibiting VEGF-induced VEGFR-2 signaling pathway. PatholRes Pract. 2020,216(8): 153031.
(7)Jinhuan Jiang, Jiang Pi, Hua Jin, Jiye Cai. Oridonin-induced mitochondria- dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/Mtor and Ras/Raf pathways.J Cell Biochem. 2019,120(3): 3736-3746.
(8)Jinhuan Jiang, Jiang Pi, Hua Jin, Fen Yang, Jiye Cai. Chinese herb medicine matrine induce apoptosis in human esophageal squamous cancer KYSE-150 cells through increasing reactive oxygen species and inhibiting mitochondrial function.Pathol Res Pract. 2018,214(5): 691-699.
(9)Jinhuan Jiang, Jiang Pi, Jiye Cai. Theadvancing ofzincoxidenanoparticles forbiomedicalapplications. Bioinorg Chem Appl. 2018,2018:1062562.
(10)Jinhuan Jiang, Jiang Pi, Hua Jin, Jiye Cai. Functional graphene oxide as cancer-targeted drug delivery system to selectively induce oesophageal cancer cell apoptosis. Artif Cells Nanomed Biotechnol. 2018, S3:297-30.
(11) Jiang Pi*,Jinhuan Jiang*, Huaihong Cai, Fen Yang, Hua Jin, Peihui Yang, Jiye Cai and Zheng W. Chen.GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways. DRUG DELIVERY, 2017. VOL. 24, NO. 1, 1549–1564
(12)Jiang JH, Yao S, Cai HH, Yang PH, Cai J.Synthesis and synergetic effects of chrysin-organogermanium (IV)complex as potential anti-oxidant. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5727-5732.
(13)Jiang JH, Jin H, Liu L, Pi J, Yang F, Cai J. Curcumin disturbed cell-cycle distribution of HepG2 cells via cytoskeletal arrangement.Scanning. 2013 Jul-Aug;35(4):253-260.
(14)Zhang L,Jiang JH, Luo JJ, Zhang L, Cai JY, Teng JW, Yang PH.A label-free electrochemiluminescence cytosensors for specific detection of early apoptosis.Biosens Bioelectron. 2013 Nov 15;49:46-52.
(15)江金環，張海濤，楊曉燕，孫少衛，郭紫芬.立德樹人視野下藥理學課程思政教育的探索，中國高等醫學教育,2021(03):19-20.
(16)江金環，蘇波，張海濤，楊曉燕，孫少衛，王姝之，郭紫芬.以學生為中心的BOPPPS教學模式下藥理學課程思政教學設計，衛生職業教育，2022.