王佶恺

一、基本情況

王佶恺，博士，副教授，2003网站太阳集团校聘教授，碩士生導師，湖南省青年骨幹教師，衡陽市領軍人才，中山大學訪問學者。2014年畢業于中國藥科大學2003网站太阳集团，獲藥學學士學位，後于湖南大學（化學生物傳感與計量學國家重點實驗室）進行生化分析技術研究，2019年獲得化學博士學位，同年在National University of Singapore進行訪學交流，後入職2003网站太阳集团。主要研究方向為基于納米生化傳感器的藥物分析新方法開發，以及納米生物成像技術的研究。主持了包括國家自然科學基金青年項目、湖南省教育廳優秀青年項目、湖南省自然科學基金青年項目等在内的多項國家和省部級課題。以第一作者/通訊作者身份在Journal of Hazardous Materials, Trends in Environmental Analytical Chemistry, Journal of Nanobiotechnology, Nano Letters, ACS Applied Materials & Interfaces，Analytical Chemistry, Journal of Pharmaceutical Analysis，Chemical Communications等期刊上發表10餘篇高水平SCI論文，其中中科院一區論文10篇，并擔任ACS Nano，Analytical Chemistry，Sensors and Actuators B: Chemical等SCI的審稿人。

Email: jkwang@hnu.edu.cn

二、研究領域

1.藥物分析：基于功能納米材料的藥物和醫學檢驗新方法的開發。

2.藥劑學：生物醫學材料合成設計與診療一體化探針的研究。

三、工作及學習經曆

2020/3-至今，2003网站太阳集团，2003网站太阳集团，副教授（校聘教授）

2015/9-2019/10，湖南大學，化學化工學院，博士

2014/8-2015/5，湖南省藥品檢驗研究院，藥師

2010/9-2014/7，中國藥科大學，2003网站太阳集团，本科

2004/9-2010/6，衡陽市第八中學，中學

四、社會兼職

全國研究生教育評估監測專家庫專家。美國化學學會會員，湖南省藥學會會員。ACS Nano，Analytical Chemistry，Sensors and Actuators B: Chemical等SCI的審稿人。Interdisciplinary Medicine，Science Journal of Chemistry等雜志青年編委。

五、教學工作

承擔2003网站太阳集团課程：藥物分析學、藥劑學、藥用高分子材料、生藥學、藥學前沿與進展（拔尖班）、新藥研發與新藥申報（研究生）。

六、承擔課題

1.國家自然科學基金青年，32301161，光/炎症共激活型熒光納米探針的設計及其原位高時空分辨成像的研究，2024/01-2026/12，主持

2.湖南省教育廳優秀青年項目，22B0455，新型矽基熒光納米晶标記的突變敏感型SARS-COV-2核酸檢測，2023/01-2025/12，主持

3.湖南省自然科學基金青年項目，2021JJ40452，基于電子俘獲-近紅外激勵發光效應的高亮硫氧化钆納米晶的病原體快速檢測和活體診療研究，2021/01-2023/12，主持

4.湖南省衛生健康委科研課題，202112062218，基于超高紅外轉換效率镧系納米晶的病原體便攜檢測和活體診療研究，2021/01-2023/12，主持

七、代表性文章

1. Zhu, Yanli; Wang, Jikai(Corresponding author); Pengfei Zeng;et al. Novel Ag-modified vanadate nanosheets for determination of small organic molecules with laser desorption ionization mass spectrometry,Journal ofHazardous Materials, 2023, 464(2024): 132986.

2. Zhu, Yanli; Wang, Jikai(Corresponding author); Chengxiao Fu;et al. Temporally and Spatially Resolved Molecular Profiling in Fingerprint Analysis Using Indium Vanadate Nanosheets-Assisted Laser Desorption Ionization Mass Spectrometry,Journal of Nanobiotechnology, 2023, 21, 475.

3. Zhu, Yanli; Wang, Jikai (Corresponding author); Xie, Haitao;et al. Double Signal Amplification Strategy for Dual-Analyte Fluorescent Aptasensor to Visualizing Cancer Biomarker Proteins.Analytical Chemistry, 2022, 94(29): 10451-10461.

4. Zhu, Yanli; Wang, Jikai (Corresponding author); Xie, Haitao;et al. NIR-to-Vis handheld platforms for detecting miRNA level and mutation based on sub-10 nm sulfide nanodots and HCR Amplification,ACS Applied Materials & Interfaces, 2022, 14(8): 10212-10226.

5. Zhu, Yanli; Wang, Jikai(Corresponding author); Sun, Yiyang;et al. A magneto-fluorescence bacteria assay strategy based on dual colour sulfide fluorescent nanoparticles with high near-IR conversion efficiency,Analyst, 2020, 145(13): 4436-4441.

6. Wang, Jikai(Co-corresponding author); Zeng, Pengfei; Haitao Xie;et al. An economical and flexible chip using surface-enhanced infrared absorption spectroscopy for pharmaceutical detection: combining qualitative analysis and quantitative detection,Journal of Pharmaceutical Analysis, https://doi.org/10.1016/j.jpha.2024.101076.

7. Wang, Jikai(Co-corresponding author); Xie, Zhulan; Zhu, Yanli;et al. Surface-enhanced infrared absorption spectroscopy (SEIRAS) for biochemical analysis: Progress and perspective,Trends in Environmental Analytical Chemistry, 2024, 41, e00226.

8. Wang, Jikai (Co-corresponding author); Zhu, Yanli; He, Ni;et al. Tri-doped alkaline earth sulfide nanoparticles as a new class of highly efficient probe with near-IR stimulated fluorescence for in vivo and ultrasensitive bacteria targeted imaging,Sensors and Actuators B: Chemical, 2020, 305(2020): 0-127427.

9. Wang, Jikai; Zhu, Yanli; Grimes, Craig A;et al. Multicolor lanthanide-doped CaS and SrS near-infrared stimulated luminescent nanoparticles with bright emission: application in broad-spectrum lighting, information coding, and bio-imaging,Nanoscale, 2019, 11(26): 12497-12501. (IF: 6.970 (2019))

10. Wang, Jikai; Zhu, Yanli; Grimes, Craig A;et al. Eu,Sm,Mn-Doped CaS Nanoparticles with 59.3% Upconversion-Luminescence Quantum Yield: Enabling Ultrasensitive and Facile Smartphone-Based Sulfite Detection,Analytical Chemistry, 2018, 90(14): 8658-8664. (IF: 6.350 (2018))

11. Wang, Jikai; He, Ni; Zhu, Yanli;et al. Highly-luminescent Eu,Sm,Mn-doped CaS up/down conversion nano-particles: application to ultra-sensitive latent fingerprint detection and in vivo bioimaging,Chemical Communications, 2018, 54(6): 591-594. (IF: 6.164 (2018))